Tokyo, Nov. 4 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059628) titled 'Study on the Therapeutic Effects of Epipharyngeal Abrasive Therapy (EAT) and Immune Profile Changes in Chronic Nasopharyngitis' on Nov. 4.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Self control

Primary Sponsor: Institute - Mogitate Medical Corporation

Condition: Condition - Chronic Nasopharyngitis Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To quantitatively evaluate immune profile changes before and after Epipharyngeal Abrasive Therapy (EAT) in patients with chronic nasopharyngitis using flow cytometry of scraped epithelial cells and peripheral blood. The study also aims to identify disease-specific immune characteristics by comparing with healthy controls. Basic objectives2 - Others

Intervention: Interventions/Control_1 - Patients with chronic nasopharyngitis will receive Epipharyngeal Abrasive Therapy (EAT) once a week for 4 weeks. Peripheral blood and epipharyngeal swab samples will be collected before and after the intervention to evaluate changes in immune cell composition.

Eligibility: Age-lower limit - 15 years-old = Gender - Male and Female Key inclusion criteria - Participants diagnosed with chronic nasopharyngitis, aged 15 years or older, who consent to EAT and understand the study purpose and provide written informed consent. Key exclusion criteria - Individuals with severe systemic diseases, those using immunosuppressive agents, pregnant or breastfeeding women, or those deemed inappropriate by the principal investigator. Target Size - 40

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 11 Month 03 Day Anticipated trial start date - 2025 Year 11 Month 04 Day Last follow-up date - 2026 Year 11 Month 03 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068199

Disclaimer: Curated by HT Syndication.