Tokyo, June 11 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061857) titled 'Incremental diagnostic value of pericoronary adipose tissue attenuation for the detection of vulnerable plaques' on June 10.
Study Type:
Observational
Primary Sponsor:
Institute - Others
Condition:
Condition - Acute coronary syndrome
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - This study also aims to evaluate whether adding PCAT attenuation to morphological and physiological CT-derived indices improves the discrimination and reclassification of ACS culprit lesions with plaque rupture.
Basic objectives2 - Others
Eligibility:
Age-lower limit - 20
years-old
=
Gender - Male and Female
Key inclusion criteria - 1. Patients who developed acute coronary syndrome (ACS) due to plaque rupture as defined by percutaneous coronary intervention performed at the participating institutions between January 1, 2016 and December 31, 2025.
2. Patients in whom plaque rupture at the culprit lesion was identified by intravascular imaging, including intravascular ultrasound and/or optical coherence tomography, at the time of ACS.
2. Among the above patients, those who underwent coronary CT between 1 month and 2 years before the onset of ACS.
Key exclusion criteria - 1. Patients who developed ACS due to restenosis-related lesions.
2. Patients who underwent coronary artery bypass grafting.
3. Patients with inadequate image quality on coronary CT.
Target Size - 150
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2026 Year 06 Month 10 Day
Anticipated trial start date - 2026 Year 08 Month 01 Day
Last follow-up date - 2028 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070779
Disclaimer: Curated by HT Syndication.
