Tokyo, Jan. 21 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060412) titled 'Integrated Analysis of Radiomics and Molecular Profiling in malignant tumors' on Jan. 20.

Study Type: Observational

Primary Sponsor: Institute - National Cancer Center Hospital East

Condition: Condition - malignant tumor Classification by malignancy - Malignancy Genomic information - YES

Objective: Narrative objectives1 - By analyzing CT/MRI and other radiological image data obtained from malignant tumor patients enrolled in studies collecting such data (see below) within the SCRUM-MONSTAR-related research-a molecular profiling platform for malignant tumors-we elucidate the radiological image profiles in malignant tumor patients. Furthermore, by analyzing the relationship between the radiological imaging profile and clinical information obtained from the SCRUM-MONSTAR-related research-including clinical pathological factors, clinical course (treatment history, response rate, progression-free survival, treatment success period, overall survival, etc.)-and molecular profiles (gene abnormalities, gene expression, tumor microenvironment, etc.), we will create a biomarker that integrates the radiological imaging profile. UMIN000039205-GALAXY Trial: Registry Study for Curatively Resectable Colorectal Cancer UMIN000053975-MONSTARSCREEN-3: Multicenter Collaborative Study Aiming to Elucidate Spatiotemporal Molecular Profiles in Malignant Tumor Patients jRCTs031220342-ENSEMBLE: Multicenter Randomized Phase III Trial Comparing Short-Course Radiotherapy with CAPOX vs. Short-Course Radiotherapy with CAPOXIRI as Neoadjuvant Therapy for Locally Advanced Rectal Cancer --IDEAL-TRJapan: International Multicenter Observational Study to Identify Early Clinical Features Indicating True Response at Reassessment Following TNT for Locally Advanced Rectal Cancer Basic objectives2 - Others

Eligibility: Age-lower limit - 18 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - 1).Regarding participation in the main study and secondary use of information, consent has not been withdrawn or refused for that study. 2).Radiological imaging data is being collected in the main study. Key exclusion criteria - The researcher is deemed unqualified. Target Size - 9000

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2016 Year 01 Month 09 Day Date of IRB - 2026 Year 01 Month 09 Day Anticipated trial start date - 2026 Year 01 Month 19 Day Last follow-up date - 2031 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068097

Disclaimer: Curated by HT Syndication.