Tokyo, July 26 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058602) titled 'Investigating the Relationship Between Air Pollution and Ocular Diseases' on July 25.
Study Type:
Interventional
Study Design:
Basic Design - Parallel
Randomization - Non-randomized
Blinding - Open -but assessor(s) are blinded
Control - Active
Primary Sponsor:
Institute - Tsurumi University
Condition:
Condition - ocular disease
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - The objective of this study is to clarify the relationship between exposure to air pollutants particularly volatile organic compounds and fine particulate matter and the development or progression of ocular diseases such as age related macular degeneration dry eye disease conjunctivitis and diabetic retinopathy This research aims to evaluate both epidemiological associations and underlying biological mechanisms with a focus on oxidative stress and inflammatory responses induced by air pollution Additionally ocular surface infections will be investigated through ocular surface washes and the culture of particles collected from the eyelid margins
Basic objectives2 - Efficacy
Intervention:
Interventions/Control_1 - eyewash
Interventions/Control_2 - Bike commuting or car commuting
Eligibility:
Age-lower limit - 12
years-old
=
Gender - Male and Female
Key inclusion criteria - Subjects with ocular disease or ocular symptoms
Key exclusion criteria - 1 Subjects with a past history of ocular surgery.
2. Subjects who can not use eyewash solution.
Target Size - 30
Recruitment Status:
Recruitment status - Enrolling by invitation
Date of protocol fixation - 2025 Year 04 Month 01 Day
Date of IRB - 2025 Year 06 Month 25 Day
Anticipated trial start date - 2025 Year 08 Month 01 Day
Last follow-up date - 2030 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067006
Disclaimer: Curated by HT Syndication.
