Tokyo, April 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060935) titled 'Investigation of Humoral Factors in the Pathogenesis of Acquired Kidney Diseases' on April 1.
Study Type:
Observational
Primary Sponsor:
Institute - Kyorin University
Condition:
Condition - Idiopathic nephrotic syndrome, IgA nephropathy, membranous nephropathy, focal segmental glomerulosclerosis, lupus nephritis
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - Using serum from patients with idiopathic nephrotic syndrome and other acquired kidney diseases, we will measure anti-Crb2, anti-nephrin, and anti-sialic acid antibodies as well as related chemokine levels, and evaluate whether these humoral factors can serve as blood biomarkers for disease diagnosis and assessment of disease activity.
Basic objectives2 - Others
Eligibility:
Age-lower limit - Not applicable
Age-upper limit - Not applicable
Gender - Male and Female
Key inclusion criteria - The study will include patients diagnosed with idiopathic nephrotic syndrome or other acquired kidney diseases who have stored serum samples, as well as patients or healthy volunteers who provide written informed consent to participate in the prospective cohort study.
Key exclusion criteria - Participants who do not provide consent for participation in the study, or who have evidence of infection such as fever, will be excluded.
Target Size - 1083
Recruitment Status:
Recruitment status - Open public recruiting
Date of protocol fixation - 2026 Year 01 Month 26 Day
Date of IRB - 2026 Year 02 Month 05 Day
Anticipated trial start date - 2026 Year 02 Month 05 Day
Last follow-up date - 2027 Year 12 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069733
Disclaimer: Curated by HT Syndication.
