Tokyo, Oct. 31 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059571) titled 'Isovolumetric Relaxation Time and Pulmonary Vascular Resistance in Chronic Obstructive Pulmonary Disease (COPD): A Retrospective Single-Center Study' on Oct. 31.

Study Type: Observational

Primary Sponsor: Institute - Nippon Medical School Hospital

Condition: Condition - Chronic Obstructive Pulmonary Disease (COPD) Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The aim of this study is to determine whether right ventricular isovolumetric relaxation time (IRT) obtained by echocardiography can serve as a noninvasive indicator of pulmonary vascular resistance (PVR) measured by right heart catheterization in patients with Chronic Obstructive Pulmonary Disease (COPD) Basic objectives2 - Others

Eligibility: Age-lower limit - 20 years-old = Gender - Male and Female Key inclusion criteria - Adults aged between 20 and 80 years.

Patients diagnosed with chronic obstructive pulmonary disease (COPD) by respiratory specialists according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria.

Clinically stable condition for at least 3 months, with no need for treatment modification.

Underwent both echocardiographic and right heart catheterization (RHC) examinations for the evaluation of exertional dyspnea.

Complete and analyzable clinical, echocardiographic, and hemodynamic data available. Key exclusion criteria - Presence of diseases other than COPD that may cause pulmonary hypertension such as interstitial lung disease or chronic thromboembolic pulmonary hypertension.

Left sided heart disease including left ventricular ejection fraction =200 mL.

Incomplete data or missing parameters required for analysis.

Inability to participate due to severe mental disorders or other conditions judged by investigators. Target Size - 60

Recruitment Status: Recruitment status - No longer recruiting Date of protocol fixation - 2021 Year 04 Month 01 Day Date of IRB - 2025 Year 10 Month 01 Day Anticipated trial start date - 2021 Year 04 Month 01 Day Last follow-up date - 2025 Year 10 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068128

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