Tokyo, April 11 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061223) titled 'Japanese study therapeutic exercise for progressive supranuclear palsy' on April 10.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Open -but assessor(s) are blinded Control - No treatment

Primary Sponsor: Institute - National Hospital Organization, Higashinagoya National Hospital

Condition: Condition - Progressive supranuclear palsy Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The primary objective of this study is to evaluate the efficacy of a 2-week short-term intensive inpatient rehabilitation program in reducing the frequency of falls among patients with progressive supranuclear palsy (PSP). Basic objectives2 - Safety,Efficacy

Intervention: Interventions/Control_1 - The intervention involves 10 daily sessions of a combined exercise program (80 min/day), including 40 minutes of PT and 40 minutes of OT. Interventions/Control_2 - Patients will continue their usual home life while maintaining the medical and nursing care insurance services they were receiving prior to the start of the study.

Eligibility: Age-lower limit - 18 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Patients who meet the criteria for "probable" PSP-Richardson syndrome according to the Movement Disorder Society Evidence-Based Diagnosis of PSP. Key exclusion criteria - 1.Patients unable to walk 10 meters independently even with the use of a walking aid. 2.Patients with a history of lower limb fracture. 3.Patients with comorbidities or complications that may affect the implementation of this study. 4.Patients with a Mini-Mental State Examination (MMSE) score of 20 or less. 5.Patients who cannot complete the primary and secondary outcome measures. 6.Patients without a caregiver who can monitor the number of falls. 7.Patients deemed inappropriate for study participation by their attending physician. 8.Patients with no history of falls within the past month. Target Size - 40

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2024 Year 11 Month 18 Day Date of IRB - 2024 Year 11 Month 18 Day Anticipated trial start date - 2026 Year 05 Month 01 Day Last follow-up date - 2029 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070011

Disclaimer: Curated by HT Syndication.