Tokyo, Aug. 5 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058679) titled 'Management and Prognosis of Cervical Lymph Node and Parotid Gland Metastases from Sebaceous Carcinoma of the Eyelid: A Systematic Review and Meta-analysis' on Aug. 5.

Study Type: Others,meta-analysis etc

Primary Sponsor: Institute - Faculty of Medicine, Niigata University, Niigata, Japan

Condition: Condition - Cervical Lymph Node and Parotid Gland Metastases from Sebaceous Carcinoma of the Eyelid Classification by malignancy - Malignancy Genomic information - NO

Objective: Narrative objectives1 - This study will be conducted in accordance with PRISMA 2020 guidelines as a systematic review and meta-analysis. A comprehensive search will be conducted in PubMed, Web of Science, and Ichushi for English-and Japanese language articles published since 2000 that report on the treatment and outcomes of cervical lymph node or parotid gland metastases from eyelid sebaceous carcinoma. Basic objectives2 - Others

Eligibility: Age-lower limit - Not applicable Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Population Patients with sebaceous carcinoma of the eyelid who developed cervical lymph node and/or parotid gland metastases. Intervention / Exposure Surgical management including parotidectomy, neck dissection, and/or postoperative radiotherapy. Outcomes Studies reporting at least one of the following: Local recurrence rate Overall survival (OS) Disease-free survival (DFS) Study Design Case reports, case series, retrospective cohort studies, or other observational studies. Language Articles published in English and Japanese Publication Year Studies published from 2000 onward. Key exclusion criteria - Primary site other than eyelid Studies on extraocular sebaceous carcinoma (e.g., trunk, scalp). No relevant metastasis Studies that do not describe cervical lymph node or parotid gland involvement. Lack of treatment or outcome data Articles that do not report surgical details or oncologic outcomes. Non-human studies, reviews, conference abstracts, editorials, or letters without original patient data. Duplicate publications When multiple reports describe the same patient cohort, only the most comprehensive report will be included.

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 08 Month 01 Day Anticipated trial start date - 2025 Year 08 Month 01 Day Last follow-up date - 2025 Year 12 Month 01 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067097

Disclaimer: Curated by HT Syndication.