Tokyo, April 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060998) titled 'Diagnostic accuracy of myocardial perfusion imaging (PET, CTP, CMR, SPECT) for coronary artery disease: a systematic review and meta-analysis using FFR/iFR as the reference standard' on April 1.
Study Type:
Others,meta-analysis etc
Primary Sponsor:
Institute - Yokohama City University
Condition:
Condition - coronary artery disease
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - To estimate the diagnostic accuracy of myocardial perfushion imaging including PET, dynamic CT perfushion, stress perfushion CMR, and SPECT, using invasive FFR or iFR as the reference standard, with per vessel analysis as primary.
In patients with suspected coronary artery disease (CAD), we will compare the per-vessel diagnostic performance of stress myocardial perfusion imaging modalities (CTP, stress perfusion MRI, PET, and SPECT). We will reconstruct TP/FP/FN/TN tables from eligible studies and estimate modality-specific pooled sensitivity and specificity and SROC curves using a bivariate random-effects (Reitsma) model.
Basic objectives2 - Efficacy
Eligibility:
Age-lower limit - 18
years-old
<=
Age-upper limit - Not applicable
Gender - Male and Female
Key inclusion criteria - known or suspected CAD
Key exclusion criteria - child, posttransplant
Target Size - 5000
Recruitment Status:
Recruitment status - No longer recruiting
Date of protocol fixation - 2025 Year 11 Month 01 Day
Date of IRB - 2025 Year 11 Month 01 Day
Anticipated trial start date - 2025 Year 11 Month 01 Day
Last follow-up date - 2025 Year 11 Month 01 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068258
Disclaimer: Curated by HT Syndication.
