Tokyo, Oct. 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062842) titled 'Nationwide Multicenter Study of Clinical Characteristics and Treatment of Kimura Disease in the Head and Neck' on Oct. 1.

Study Type: Observational

Primary Sponsor: Institute - University of Toyama

Condition: Condition - Kimura Disease Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - Kimura disease is a relatively rare chronic inflammatory disorder that predominantly affects the head and neck region, and its clinical characteristics and optimal treatment strategies remain insufficiently understood. This nationwide multicenter study aims to collect and analyze clinical data from patients with Kimura disease involving the head and neck, including symptoms, lesion site, comorbidities, laboratory findings, treatment modalities, and clinical outcomes. The objectives are to characterize the patient demographics, clinical features, treatment patterns, and outcomes of Kimura disease in Japan and to provide evidence that may contribute to the establishment of appropriate clinical management strategies and improvement of treatment outcomes. Basic objectives2 - Efficacy

Eligibility: Age-lower limit - 5 years-old = Gender - Male and Female Key inclusion criteria - 1.Patients diagnosed with Kimura disease. The diagnosis is primarily based on histopathological findings. Patients without histopathological confirmation may also be included if the attending physician at each participating institution diagnoses Kimura disease based on a comprehensive assessment of imaging findings, laboratory findings, and clinical course. Such patients will be classified as suspected cases in this study. 2.Patients with lesions involving the head and neck region. 3.Patients who received inpatient or outpatient care at the Department of Otolaryngology Head and Neck Surgery of a participating institution between January 1, 2010 and June 30, 2026. 4.Patients who have not opted out of participation in this study. Key exclusion criteria - 1.Patients who have opted out of participation in this study. 2.Patients who are deemed inappropriate for inclusion in the study by the principal investigator or other study investigators. Target Size - 50

Recruitment Status: Recruitment status - Enrolling by invitation Date of protocol fixation - 2026 Year 10 Month 01 Day Date of IRB - 2026 Year 08 Month 31 Day Anticipated trial start date - 2027 Year 01 Month 01 Day Last follow-up date - 2028 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071935

Disclaimer: Curated by HT Syndication.