Tokyo, July 6 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062129) titled 'A prospective observational study on monosodium urate crystal deposition and local inflammation in the wall of abdominal aortic aneurysms' on July 6.
Study Type:
Observational
Primary Sponsor:
Institute - Dokkyo Medical University
Condition:
Condition - Abdominal aortic aneurysm
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - To prospectively compare preoperative dual-energy CT assessment of monosodium urate (MSU) crystal deposition with histopathological MSU identification performed by polarized light microscopy of hematoxylin-eosin (HE)-stained and De Galantha-stained sections from surgically resected specimens in patients undergoing open surgical repair for abdominal aortic aneurysm, and to evaluate concordance and local inflammatory findings.
Basic objectives2 - Others
Eligibility:
Age-lower limit - 20
years-old
<=
Age-upper limit - Not applicable
Gender - Male and Female
Key inclusion criteria - (1) Patients undergoing open surgical repair for abdominal aortic aneurysm at the Department of Cardiovascular Surgery, Dokkyo Medical University Hospital
(2) Patients from whom cardiovascular tissue containing atherosclerotic lesions can be obtained during surgery
(3) Patients who have received sufficient explanation of this study and provided written informed consent
Key exclusion criteria - Patients deemed inappropriate for study participation by the principal investigator
Target Size - 30
Recruitment Status:
Recruitment status - Enrolling by invitation
Date of protocol fixation - 2026 Year 03 Month 27 Day
Date of IRB - 2026 Year 05 Month 26 Day
Anticipated trial start date - 2026 Year 06 Month 01 Day
Last follow-up date - 2029 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071092
Disclaimer: Curated by HT Syndication.
