Tokyo, Dec. 19 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060117) titled 'PROspective randomized controlled pilot study of double-Tract jejunal reconstruction adding to subtotal stomach reconstruction for Esophageal Cancer Treatment' on Dec. 18.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Open -no one is blinded Control - No treatment

Primary Sponsor: Institute - Gifu University

Condition: Condition - esophageal cancer Classification by malignancy - Malignancy Genomic information - NO

Objective: Narrative objectives1 - Short-term Postoperative Outcomes (DTGE Incidence Rate) Basic objectives2 - Safety,Efficacy

Intervention: Interventions/Control_1 - Intervention group: Subtotal gastric reconstruction plus double-tract gastrojejunostomy (conventional method + jejunal double-tract method) Interventions/Control_2 - Control group: Conventional subtotal gastric reconstruction (conventional method)

Eligibility: Age-lower limit - 18 years-old

Gender - Male and Female Key inclusion criteria - 1) Patients scheduled to undergo radical resection with esophagectomy via thoracic manipulation for esophageal cancer or esophagogastric junction cancer at our hospital 2) Patients eligible for one-stage reconstruction 3) Patients eligible for reconstruction using a subtotal gastric tube 4) Patients for whom written consent has been obtained from the patient or their representative Key exclusion criteria - 1) Patients requiring reconstruction using the colon or small intestine 2) Unresectable cases with distant metastasis (Stage IVb) or cases with T4a tumor invasion depth before chemotherapy and a high risk of postoperative mediastinal recurrence 3) Patients planning for two-stage reconstruction 4) Patients undergoing retrosternal reconstruction 5) Patients with a history of curative (chemo)radiotherapy for esophageal or pharyngeal cancer 6) Patients deemed inappropriate for research by the attending physician Target Size - 15

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 12 Month 31 Day Date of IRB - 2025 Year 12 Month 31 Day Anticipated trial start date - 2026 Year 01 Month 10 Day Last follow-up date - 2030 Year 12 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068756

Disclaimer: Curated by HT Syndication.