Clinical Trial: Randomized Controlled Trial Comparing the Effects of Cognitive Training, Physical Exercise, and Behavioral Therapy on Apathy in Post-Stroke Patients (Japan)

Tokyo, Aug. 2 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058477) titled 'Evaluation of the Effectiveness of Non-Pharmacological Interventions for Improving Apathy after Stroke' on Aug. 1.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Open -but assessor(s) are blinded Control - Active

Primary Sponsor: Institute - Kawasaki University of Medical Welfare

Condition: Condition - Post-stroke apathy Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - This study aims to compare the effectiveness of three non-pharmacological interventions: cognitive training, physical exercise, and behavioral therapy for improving post-stroke apathy and to identify the most beneficial approach. Basic objectives2 - Others

Intervention: Interventions/Control_1 - Cognitive training will be provided for 40 minutes per day, 5 days per week, for 2 weeks (total 10 sessions). Training includes visual scanning tasks, verbal fluency tasks, and constructional tasks. The intervention will be administered by clinical rehabilitation staff. Interventions/Control_2 - Physical exercise will be conducted for 40 minutes per day, 5 days per week, for 2 weeks (total 10 sessions). The intervention includes sit-to-stand training, gait training, and muscle strengthening exercises. The intervention will be administered by clinical rehabilitation staff.

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - Ability to provide written informed consent, Aged between 18 and 79 years, Right-handed, MMSE score of 23 or higher, AES score of 37 or higher, Diagnosed with post-stroke apathy within 3 months after stroke onset Key exclusion criteria - Patients with severe systemic diseases that hinder participation in rehabilitation, or with psychosis, depression, disturbance of consciousness, or hearing or visual impairments that interfere with assessment. Target Size - 42

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 08 Month 01 Day Anticipated trial start date - 2025 Year 08 Month 01 Day Last follow-up date - 2028 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000066640

Disclaimer: Curated by HT Syndication.