Tokyo, March 17 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060947) titled 'Study on Reconstruction Methods and Reflux Symptoms After Minimally Invasive Proximal Gastrectomy for Upper Gastric and Esophagogastric Junction Cancer' on March 16.

Study Type: Observational

Primary Sponsor: Institute - Yokohama City University

Condition: Condition - Proximal gastric cancer or Siewert Type II esophagogastric junction cancer Classification by malignancy - Malignancy Genomic information - NO

Objective: Narrative objectives1 - To evaluate the incidence and timing of postoperative reflux esophagitis and anastomotic stricture after proximal gastrectomy for upper gastric cancer and esophagogastric junction cancer, as well as treatment interventions for esophagitis and stricture, quality of life, and nutritional status. Basic objectives2 - Safety,Efficacy

Eligibility: Age-lower limit - 20 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - 1. Patients with histologically confirmed pStage I-III common-type upper gastric cancer or esophagogastric junction cancer. Esophagogastric junction cancer was limited to cases up to Siewert type II that were resected and reconstructed using an abdominal approach alone. 2. Patients who underwent minimally invasive proximal gastrectomy (laparoscopic or robot-assisted) with R0 resection. 3. Age: 20 years or older at the time of surgery. 4. Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 at the time of registration. 5. Patients within 5 years after surgery for the primary disease. 6. No restriction on sex. 7. Surgeon criteria: either the primary surgeon or the assistant must be certified by the Endoscopic Surgical Skill Qualification System of the Japan Society for Endoscopic Surgery (JSES). Key exclusion criteria - 1. Patients judged to be inappropriate for inclusion in this study by the principal investigator or a sub-investigator. 2. Patients who underwent combined resection of other organs, except for cholecystectomy performed for cholelithiasis. Target Size - 1100

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 02 Month 27 Day Anticipated trial start date - 2026 Year 02 Month 27 Day Last follow-up date - 2027 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069748

Disclaimer: Curated by HT Syndication.