Tokyo, July 23 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058542) titled 'Relationship between excitatory and inhibitory changes in primary somatosensory cortex and somatosensory function of fingers following transcutaneous auricular vagus nerve stimulation of the left cymba concha' on July 22.

Study Type: Interventional

Study Design: Basic Design - Cross-over Randomization - Randomized Blinding - Single blind -participants are blinded Control - Placebo

Primary Sponsor: Institute - Graduate School, Niigata University of Health and Welfare

Condition: Condition - healthy adults Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To clarify the relationship between changes in excitatory and inhibitory activity in the primary somatosensory cortex induced by taVNS and changes in somatosensory function in the fingers. Basic objectives2 - Bio-equivalence

Intervention: Interventions/Control_1 - Stimulus condition: 25 hertz,300 microsecond, below pain threshold Stimulation time: 15 min The stimulation site: The left cymba concha Interventions/Control_2 - Stimulus condition: 25 hertz,500 microsecond, below pain threshold Stimulation time: 15 min The stimulation site: The left cymba concha

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - We are looking for individuals who are interested in this research and are willing to participate voluntarily. We also invite students and graduate students enrolled in Niigata University of Health and Welfare to join us by e-mail. Key exclusion criteria - Those with neurological or psychiatric diseases, those taking medication, and those with a history of external ear injury. Target Size - 30

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 07 Month 18 Day Anticipated trial start date - 2025 Year 08 Month 21 Day Last follow-up date - 2027 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000066940

Disclaimer: Curated by HT Syndication.