Tokyo, Sept. 15 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059043) titled 'Research on Novel Biomarkers and Therapeutic Target Molecules for Urological Cancers' on Sept. 15.

Study Type: Observational

Primary Sponsor: Institute - Fukushima Medical University

Condition: Condition - Genitourinary Cancer Classification by malignancy - Malignancy Genomic information - YES

Objective: Narrative objectives1 - Urological cancers, including renal cell carcinoma, urothelial carcinoma of the renal pelvis and bladder, testicular cancer, and prostate cancer, are generally considered to have more favorable prognoses compared with many other malignancies. However, for patients who are not candidates for surgery or who experience disease recurrence, the effectiveness of chemotherapy remains limited. In this context, research efforts have focused on identifying molecular markers useful for early diagnosis and prediction of treatment resistance.

Our group has previously developed antibodies that can be applied to diagnosis and research, and we have demonstrated their potential utility as novel biomarkers. Building on these achievements, the present study aims to explore molecular targets associated with early detection and prognosis in renal cell carcinoma, urothelial carcinoma of the renal pelvis and bladder, testicular cancer, and prostate cancer. Furthermore, we will develop antibodies against these molecules to establish new diagnostic methods.

Through this research, we aim:

To contribute to improved patient outcomes by facilitating the early detection of surgically treatable cancers.

To enable personalized treatment selection by developing prognostic biomarkers that predict clinical outcomes. Basic objectives2 - Safety,Efficacy

Eligibility: Age-lower limit - Not applicable Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Patients with genitourinary cancer Key exclusion criteria - none Target Size - 500

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2021 Year 09 Month 01 Day Date of IRB - 2021 Year 08 Month 31 Day Anticipated trial start date - 2021 Year 09 Month 01 Day Last follow-up date - 2026 Year 08 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067538

Disclaimer: Curated by HT Syndication.