Tokyo, July 31 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058646) titled 'Research on periodontal treatment using hydrogen peroxide photolysis' on July 30.

Study Type: Interventional

Study Design: Basic Design - Factorial Randomization - Randomized Blinding - Open -but assessor(s) are blinded Control - Active

Primary Sponsor: Institute - Nihon University School of Dentistry at Matsudo

Condition: Condition - Periodontitis Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - We will examine the effectiveness of periodontal treatment combined with hydrogen peroxide photolysis technology in improving clinical parameters of periodontal disease and consider the usefulness of Blue Radical P-01. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Blue Radical P-01 is used in combination with subgingival SRP using a hand scaler under local anesthesia. Interventions/Control_2 - Ultrasonic scaler is used in combination with subgingival SRP using a hand scaler under local anesthesia.

Eligibility: Age-lower limit - 20 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Stage III/IV periodontitis patients have at least 3 teeth with 6 mm PD or more Key exclusion criteria - 1. smokers 2. having received antibiotic therapy and/or subgingival periodontal therapy in the previous 12 weeks 3. uncontrolled diabetes 4. presence of acute symptoms 5. taking medication affecting the periodontal condition (ex, phenytoin, nifedipine, or cyclosporine A) 6. pregnancy or breastfeeding 7. patients with pacemakers 8. patients with acatalasemia Target Size - 94

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2025 Year 01 Month 20 Day Date of IRB - 2025 Year 02 Month 28 Day Anticipated trial start date - 2025 Year 03 Month 01 Day Last follow-up date - 2030 Year 02 Month 27 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000065563

Disclaimer: Curated by HT Syndication.