Tokyo, Dec. 2 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059937) titled 'Research study on changes in blood sugar levels, weight, and body fat due to mulberry green juice' on Dec. 1.
Study Type:
Interventional
Study Design:
Basic Design - Single arm
Randomization - Non-randomized
Blinding - Open -no one is blinded
Control - Uncontrolled
Primary Sponsor:
Institute - Other
Condition:
Condition - Target condition (Condition) Healthy subjects and pre-symptomatic subjects (pre-metabolic syndrome, subjects with high blood glucose levels)
Classification by specialty Internal Medicine (Metabolism / Endocrinology)
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - The purpose of this study is to exploratorily evaluate the effects of 4-week continuous intake of "Tenku Kuwa Aojiru" (Mulberry Green Juice) on biomarkers related to metabolic syndrome and diabetes (specifically postprandial blood glucose), as well as body weight and body fat percentage. Focusing on the effect of iminosugars, a component unique to mulberry leaves, to moderate sugar absorption, this pilot study verifies its usefulness in healthy individuals and those in the borderline range.
Basic objectives2 - Safety,Efficacy
Intervention:
Interventions/Control_1 - Consumption of the test food "Tenku Kuwa Aojiru" (3g/pack) once daily for 4 weeks.
Eligibility:
Age-lower limit - 20
years-old
=
Gender - Male
Key inclusion criteria - Males and females in their 20s to 70s
Subjects who understand the purpose and content of this study and provide written informed consent
(Blood glucose group only) Subjects capable of participating in blood sampling at the designated location
(Body weight group only) Subjects capable of measuring and recording body weight and body fat percentage at home
Key exclusion criteria - Subjects with a history of serious diseases such as kidney disease
Subjects taking medications or supplements unsuitable for the study
Subjects who are pregnant, lactating, or possibly pregnant
Subjects with an allergy to mulberry leaves
Subjects currently receiving treatment for diabetes (insulin injections or oral hypoglycemic agents)
Other subjects deemed inappropriate by the principal investigator
Target Size - 110
Recruitment Status:
Recruitment status - Open public recruiting
Date of protocol fixation - 2025 Year 11 Month 15 Day
Date of IRB - 2025 Year 11 Month 21 Day
Anticipated trial start date - 2025 Year 11 Month 21 Day
Last follow-up date - 2026 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068546
Disclaimer: Curated by HT Syndication.