Tokyo, Oct. 2 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000057496) titled 'Role of Nebulized dexmedetomidine in Reducing Patient Cough and Discomfort in Flexible Bronchoscopy: a randomized double-blind study' on Oct. 2.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Double blind -all involved are blinded Control - Placebo

Primary Sponsor: Institute - faculty of medicine - menoufia university

Condition: Condition - prospective double-blinded randomized control trial Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - the Patient discomfort to bronchoscopy Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Patients belonging to Group C (control group) received total volume of 10ml contain 4 ml of 4% lidocaine (160 mg of lidocaine)+ normal saline Interventions/Control_2 - Patients belonging to Group E (expermental group) received total volume of 10ml contain 4 ml of 4% lidocaine (160 mg of lidocaine)+ dexmedetomidine

Eligibility: Age-lower limit - 20 years-old = Gender - Male and Female Key inclusion criteria - ASA class I, II or III undergoing diagnostic procedures such as broncho-alveolar lavage, endobronchial or transbronchial biopsies, or brush cytology were permitted Key exclusion criteria - , we will not include patients requiring cryobiopsy or endobronchial ultrasound because these procedures are performed under deep sedation including fiberoptic intubation in our institution Patients on opioid therapy, central nervous system depressants, or with hepatic or renal disease, pregnancy or lactation, psychiatric disorder, and/or bleeding disorder are not included. We also excluded patients established respiratory depression; sleep apnea, a history of hypersensitivity to one of the drugs and/or not willing to participate in the study. Target Size - 30

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2024 Year 09 Month 14 Day Date of IRB - 2024 Year 09 Month 14 Day Anticipated trial start date - 2025 Year 04 Month 02 Day Last follow-up date - 2025 Year 10 Month 15 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000065696

Disclaimer: Curated by HT Syndication.