Tokyo, Oct. 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062734) titled 'The effect of co-ingesting rice and liquid on glycemic response and gastric emptying in healthy subjects' on Oct. 1.
Study Type:
Interventional
Study Design:
Basic Design - Cross-over
Randomization - Randomized
Blinding - Open -no one is blinded
Control - No treatment
Primary Sponsor:
Institute - Mukogawa Women's University
Condition:
Condition - Healthy people
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - Even when the same amount of carbohydrate energy is consumed, for example in the form of white rice or bread, postprandial glycemic responses may differ depending on how the carbohydrate is consumed. For instance, consuming vegetables (dietary fiber) before carbohydrate intake has been reported to attenuate postprandial increases in blood glucose levels. In contrast, the effects of beverage consumption after carbohydrate intake, particularly the presence or absence of beverage consumption and the timing of ingestion, on postprandial glycemia, gastric emptying, and sensations of satiety and hunger remain incompletely understood.
The present study aims to investigate, in young healthy adults, the effects of beverage consumption, including green tea and water, and the timing of beverage ingestion on postprandial gastric emptying, blood glucose responses, and subjective sensations of satiety and hunger following a single meal of white rice.
This study is expected to provide scientific evidence regarding how white rice may be consumed in relation to beverage intake, taking into account postprandial glycemic responses and gastric emptying. In addition, the findings may contribute to a better understanding of the mechanisms underlying gastric sieving of mixtures of solid food and liquids.
Basic objectives2 - Others
Intervention:
Interventions/Control_1 - 150 g white rice only
Interventions/Control_2 - 150 g of white rice followed immediately by 200 mL of water
Eligibility:
Age-lower limit - 18
years-old
=
Gender - Female
Key inclusion criteria - Young, healthy, non-pregnant Japanese females aged 18-29 years with a body mass index (BMI) less than 25 kg/m2. All participants have a blood pressure < 120/80 mmHg.
In addition, all participants are nonsmokers, had no food allergies, are not on any medication, and have no history of gastrointestinal tract, cardiovascular, or metabolic diseases.
Key exclusion criteria - Persons with food allergies, persons receiving medication in hospital, etc., or persons who have a smoking habit.
Target Size - 11
Recruitment Status:
Recruitment status - Completed
Date of protocol fixation - 2022 Year 04 Month 07 Day
Date of IRB - 2022 Year 05 Month 28 Day
Anticipated trial start date - 2022 Year 06 Month 03 Day
Last follow-up date - 2022 Year 10 Month 26 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071832
Disclaimer: Curated by HT Syndication.
