Tokyo, April 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000056612) titled 'The effect of gut microbiota on malnutrition and sarcopenia in early stroke patients' on April 1.
Study Type:
Observational
Primary Sponsor:
Institute - Graduate School of Medical Science, Kyoto Prefectural University of Medicine
Condition:
Condition - Stroke
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - This study focuses on abnormalities in the gut microbiota (intestinal flora) as a visible indicator of changes in intestinal function associated with systemic inflammation. We hypothesized that intestinal dysfunction caused by systemic inflammation following stroke promotes abnormalities in the gut microbiota, leading to the development of malnutrition and, subsequently, sarcopenia. By verifying this hypothesis and elucidating the impact of temporal changes in the gut microbiota on malnutrition and sarcopenia, we aim to develop treatment strategies to prevent the complication of sarcopenia following stroke. This forms the basis of our research plan.
Basic objectives2 - Others
Eligibility:
Age-lower limit - 18
years-old
=
Gender - Male and Female
Key inclusion criteria - Patients who can provide written consent for research participation based on their free will.
Key exclusion criteria - Female patients who are pregnant or may be pregnant, patients with a cardiac pacemaker, patients with severe dementia, patients with foreign nationalities other than Japanese, and cases deemed inappropriate by the attending physician.
Target Size - 120
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2026 Year 04 Month 01 Day
Anticipated trial start date - 2026 Year 04 Month 01 Day
Last follow-up date - 2028 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000063857
Disclaimer: Curated by HT Syndication.
