Tokyo, Nov. 15 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063133) titled 'The effect of short-term hypoxia inhalation on subsequent endurance performance' on Nov. 15.

Study Type: Interventional

Study Design: Basic Design - Cross-over Randomization - Randomized Blinding - Single blind -participants are blinded Control - Placebo

Primary Sponsor: Institute - Niigata University of Health and Welfare

Condition: Condition - Healthy younger Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To explore the effect of short-term hypoxia inhalation on subsequent endurance performance and the relationship between hypoxia-induced change in endurance performance and cardiac autonomic nerve activity. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Participants are exposed to normobaric hypoxia (FiO2 = 0.13) for 10 min while sitting at rest. After hypoxia inhalation, participants perform incremental exercise on a recumbent ergometer under normoxic conditions. The workload is increased by 20 W/min for males and 15 W/min for females until participants can no longer maintain the required pedaling rate. Interventions/Control_2 - Participants rest for 10 min under normoxic conditions. After hypoxia inhalation, participants perform incremental exercise on a recumbent ergometer under normoxic conditions. The workload is increased by 20 W/min for males and 15 W/min for females until participants can no longer maintain the required pedaling rate.

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - Males and females aged 18-30 years old affiliated with Niigata University of Health and Welfare. Participants must have no history of neurological, respiratory, circulatory, musculoskeletal, or metabolic disorders. They must be nonsmokers. They must not have engaged in high-altitude training, hypoxic training, or lived at high altitudes within the past six months. Their levels of depression and sleep quality, as assessed by a questionnaire, must be within normal ranges. They must have stable lifestyle habits. Key exclusion criteria - Individuals under 18 years of age or 31 years of age or older. Individuals with a history of neurological, respiratory, circulatory, musculoskeletal, or metabolic disorders. Smokers. Individuals who have engaged in high-altitude training, hypoxic training, or lived at high altitudes within the past six months. Individuals whose levels of depression and sleep quality, as assessed by the questionnaire, exceed the cutoff values. Individuals with unstable lifestyle habits. Target Size - 25

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 10 Month 01 Day Anticipated trial start date - 2026 Year 12 Month 15 Day Last follow-up date - 2027 Year 06 Month 30 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072201

Disclaimer: Curated by HT Syndication.