Tokyo, Nov. 10 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059704) titled 'Using Virtual Reality to Help Reduce Anxiety Before Oral Surgery' on Nov. 10.
Study Type:
Interventional
Study Design:
Basic Design - Parallel
Randomization - Randomized
Blinding - Open -no one is blinded
Control - No treatment
Primary Sponsor:
Institute - Universitas Padjadjaran
Condition:
Condition - Preoperative anxiety in oral surgery patients
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - The objective of this study is to evaluate the effectiveness of virtual reality in reducing preoperative anxiety among patients undergoing minor oral surgery. This will be assessed using changes in salivary alpha-amylase and cortisol levels, as well as the Amsterdam Preoperative Anxiety and Information Scale (APAIS)
Basic objectives2 - Efficacy
Intervention:
Interventions/Control_1 - Virtual Reality Relaxation
Participants in the intervention group received a 15-minute immersive Virtual Reality (VR) session immediately prior to minor oral surgery under general anesthesia. The VR content featured a relaxing beach environment with calming background sounds. The session was delivered using a head-mounted display (Oculus Go), with the same video and duration used for all participants to ensure standardization.
Duratioin 15 minutes, one-time session
Interventions/Control_2 - Standard Preoperative Procedure (Control Group)
Eligibility:
Age-lower limit - 18
years-old
=
Gender - Male and Female
Key inclusion criteria - Adults aged 18 to 45 years
Scheduled for elective minor oral surgery under general anesthesia
Able to understand the study procedures and provide informed consent
Able to read and complete the APAIS questionnaire
No prior exposure to virtual reality
Key exclusion criteria - History of psychiatric or neurological disorders
Use of medications affecting stress hormones in the last 7 days (e.g., corticosteroids, anxiolytics)
Systemic diseases that may affect saliva biomarkers (e.g., diabetes, adrenal disorders)
Current or past substance abuse (alcohol, drugs)
Pregnant or breastfeeding
Visual, vestibular, or balance disorders that interfere with VR usage
Allergy to materials used for saliva collection
Unwilling or unable to comply with study procedures
Target Size - 30
Recruitment Status:
Recruitment status - No longer recruiting
Date of protocol fixation - 2024 Year 12 Month 01 Day
Date of IRB - 2023 Year 12 Month 15 Day
Anticipated trial start date - 2025 Year 01 Month 01 Day
Last follow-up date - 2025 Year 07 Month 01 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068285
Disclaimer: Curated by HT Syndication.