Tokyo, Dec. 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000052831) titled 'The features of pain threshold in Parkinson's syndrome' on Nov. 30.

Study Type: Observational

Primary Sponsor: Institute - Saitama Medical University Hospital

Condition: Condition - Parkinson's disease, multiple system atrophy, progressive supranuclear palsy Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - Patients with Parkinson's disease (PD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and other Parkinsonian syndromes often complain of pain, which is closely associated with a decreased quality of life. Although it has been reported that PSP patients complain of pain less frequently than PD and MSA patients, few reports have examined this in detail. However, the Pain Vision pain quantification system (Pain Vision), which was developed by Nipro Corporation in 2013 to quantitatively evaluate pain, has been put to practical use, making it possible to objectively evaluate pain. In this study, we measured pain thresholds using Pain Vision in patients with three typical Parkinson's syndromes (PD, MSA, and PSP), and examined the characteristics of the pain thresholds. Basic objectives2 - Others

Eligibility: Age-lower limit - 20 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - PD group: patients with Parkinson's disease aged 20 years or older (meet the MDS diagnostic criteria 2015 for "clinically certain Parkinson's disease". MSA group: patients with multiple system atrophy aged 20 years and older (meet the Gilman classification second consensus criteria "Probable". PSP group: Patients with progressive supranuclear palsy aged 20 years or older (meet the NINDS-SPSP diagnostic criteria for "Probable"). Normal subjects: Normal subjects without underlying disease. Key exclusion criteria - MMSE score of 27 or lower Target Size - 80

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2023 Year 01 Month 01 Day Date of IRB - 2023 Year 01 Month 30 Day Anticipated trial start date - 2023 Year 01 Month 30 Day Last follow-up date - 2025 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000057138

Disclaimer: Curated by HT Syndication.