Tokyo, Nov. 13 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059744) titled 'To verify the analgesic effect of intraoperative pulsed radiofrequency therapy during thoracic surgery to alleviate postoperative pain' on Nov. 12.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Non-randomized Blinding - Open -no one is blinded Control - No treatment

Primary Sponsor: Institute - St. Lukes International University

Condition: Condition - Lung cancer, Mediastinum tumor, Pneumothorax, Chest wall tumor, Valvular heart disease Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To reduce postoperative pain without adverse effects and to decrease the amount of postoperative analgesics used by performing Pulsed Radiofrequency (PRF), which has been reported to have safety and analgesic efficacy, during the perioperative period in patients undergoing respiratory and cardiovascular surgery. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Group Receiving PRF During Surgery Interventions/Control_2 - Conventional Pain Management Group

Eligibility: Age-lower limit - 18 years-old

Gender - Male and Female Key inclusion criteria - Inclusion Criteria for the Study Group:

Individuals deemed suitable for thoracoscopic, robot-assisted thoracoscopic, or open thoracic surgery. Age between 18 and 84 years at the time of consent. Written informed consent has been obtained from the individual for participation in the study. Criteria for the Control Group:

Individuals who underwent thoracoscopic, robot-assisted thoracoscopic, or open thoracic surgery at our hospital between April 2023 and March 2024. Key exclusion criteria - Exclusion Criteria for the Study Group:

Individuals with a pacemaker that may cause electrical interference. Women who are pregnant, breastfeeding, or have the possibility of pregnancy. Individuals deemed inappropriate for the study by the principal investigator or co-investigators. Exclusion Criteria for the Control Group:

Individuals who have submitted a statement of non-participation. Target Size - 290

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2024 Year 08 Month 23 Day Date of IRB - 2024 Year 09 Month 09 Day Anticipated trial start date - 2024 Year 10 Month 01 Day Last follow-up date - 2026 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000063344

Disclaimer: Curated by HT Syndication.