Tokyo, March 10 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060799) titled 'Diagnostic validity of tertiary lymphoid structure (TLS) evaluation using transbronchial cryobiopsy (TBCB) specimens in non-small cell lung cancer: A retrospective study comparing with surgical specimens' on March 10.
Study Type:
Observational
Primary Sponsor:
Institute - Hakodate Goryoukaku Hospital
Condition:
Condition - Non-small cell carcinoma
Classification by malignancy - Malignancy
Genomic information - NO
Objective:
Narrative objectives1 - To clarify the concordance of tertiary lymphoid structure (TLS) evaluation (presence and maturity) using transbronchial cryobiopsy (TBCB) specimens with the gold standard surgical specimens in patients with non-small cell lung cancer, and to validate TBCB as a preoperative diagnostic method.
Basic objectives2 - Others
Eligibility:
Age-lower limit - 18
years-old
Gender - Male and Female
Key inclusion criteria - Patients with non-small cell lung cancer who underwent transbronchial cryobiopsy (TBCB) for preoperative diagnosis at our hospital
Patients who subsequently underwent surgical resection of the primary lesion
Patients whose medical records and preserved pathological specimens (paraffin blocks) are available for analysis
Key exclusion criteria - Cases with insufficient specimen volume for pathological evaluation (presence and maturity of TLS)
Cases that received preoperative chemotherapy or radiotherapy
Other cases deemed inappropriate for this study by the principal investigator
Target Size - 22
Recruitment Status:
Recruitment status - No longer recruiting
Date of protocol fixation - 2025 Year 12 Month 05 Day
Date of IRB - 2026 Year 01 Month 14 Day
Anticipated trial start date - 2026 Year 01 Month 15 Day
Last follow-up date - 2026 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069561
Disclaimer: Curated by HT Syndication.
