Tokyo, Oct. 14 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063265) titled 'Verify the differences in QST responses between those whose knee pain is and is not alleviated by spinal load' on Oct. 13.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Non-randomized Blinding - Open -no one is blinded Control - No treatment

Primary Sponsor: Institute - Secomedic hospital

Condition: Condition - Knee osteoarthritis Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The aim is to clarify the differences in responses to quantitative sensory testing between individuals with knee pain who experience improvement through lumbar spine movement, and those who do not. Basic objectives2 - Others

Intervention: Interventions/Control_1 - Participants are asked to perform active lumbar extension from the prone position. We will measure pressure pain thresholds around the knee and on the forearm, as well as temporal summation of pain and conditioned pain modulation, both before and after exercise. Interventions/Control_2 - Participants are asked to perform active lumbar extension from the prone position. We will measure pressure pain thresholds around the knee and on the forearm, as well as temporal summation of pain and conditioned pain modulation, both before and after exercise.

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - Individuals 18 years of age or older, individuals diagnosed with osteoarthritis of the knee and individuals who are capable of performing active lumbar extension exercises in a prone position. Key exclusion criteria - Individuals who are pregnant or may be pregnant; individuals diagnosed with dementia or a mental illness; individuals diagnosed with a central nervous system disorder or an intractable neurological disease that may affect their ability to exercise; individuals experiencing pain in the shoulders, hips, lower back, or other areas that may prevent them from performing the planned exercises or meeting the required frequency; and individuals who have been advised by a doctor not to exercise Target Size - 100

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 08 Month 07 Day Date of IRB - 2026 Year 09 Month 25 Day Anticipated trial start date - 2026 Year 10 Month 13 Day Last follow-up date - 2028 Year 12 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072416

Disclaimer: Curated by HT Syndication.