Tokyo, May 27 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061694) titled 'Understanding How Vision and Brain Stimulation Affect Spatial Awareness and Movement (VISTA)' on May 26.

Study Type: Interventional

Study Design: Basic Design - Cross-over Randomization - Randomized Blinding - Double blind -all involved are blinded Control - Placebo

Primary Sponsor: Institute - Kobe University

Condition: Condition - Healthy Volunteers Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The objective of this research is to elucidate the effects of prism adaptation therapy (PA) and transcranial direct current stimulation (tDCS) applied to the parietal cortex on the Where Bias and Aiming Bias, which constitute spatial cognitive biases. The Where and Aiming Components will be quantified using a line bisection task and its reverse condition, and a randomized, double-blind, crossover trial will be conducted with healthy adult participants. Study 1 aims to examine the influence of PA on the Aiming Component, whereas Study 2 investigates the effect of tDCS on the Where Component. Through these investigations, the research seeks to clarify the sensory-motor characteristics underlying spatial cognition. Basic objectives2 - Others

Intervention: Interventions/Control_1 - Study 1: Right-eye prism glasses (washout period) placebo glasses Study 2: Anodal tDCS to the right parietal lobe (washout period) sham tDCS to the parietal lobe Interventions/Control_2 - Study 1: Placebo glasses (washout period) right prism glasses Study 2: Parietal sham tDCS (washout period) right parietal anodal tDCS

Eligibility: Age-lower limit - 18 years-old

Gender - Male and Female Key inclusion criteria - - Healthy adults aged 18 to 30 years - Right-handed, confirmed by the Edinburgh Handedness Inventory - No history of neurological or psychiatric disorders - Not meeting any contraindications for tDCS (Study 2 only) - Able to understand the study procedures and provide written informed consent Key exclusion criteria - - History of neurological or psychiatric disorders - Orthopedic conditions affecting upper limb motor function - Visual impairments interfering with task performance - History of epilepsy or increased seizure risk - Contraindications for tDCS (Study 2) - Pregnant or possibly pregnant (Study 2) - Under the influence of alcohol or drugs - Deemed unsuitable by the principal investigator Target Size - 88

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 04 Month 09 Day Anticipated trial start date - 2026 Year 06 Month 01 Day Last follow-up date - 2028 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070590

Disclaimer: Curated by HT Syndication.