Tokyo, Feb. 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060426) titled 'Retrospective Observational Study Evaluating the Diagnostic Performance of a Novel Endoscopic Mode Combining NBI and TXI for Lesion Identification' on Feb. 1.

Study Type: Observational

Primary Sponsor: Institute - Saitama medical University International Medical Center

Condition: Condition - neoplastic or non-neoplastic lesions Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - Narrow Band Imaging (NBI), which utilizes short-wavelength light, provides excellent visualization of superficial mucosal microvasculature and structures and is widely used in gastrointestinal endoscopic diagnosis. However, NBI alone has inherent limitations in image brightness and color contrast, and therefore may not always provide sufficient visibility or discrimination of lesions. In contrast, Texture and Color Enhancement Imaging (TXI) is a novel image enhancement technology that performs luminance correction and color enhancement. When used in combination with conventional NBI, TXI is expected to further improve lesion visibility and discrimination. This combined approach may be particularly useful for lesions that are difficult to detect, such as flat or early-stage lesions. The aim of this study was to compare lesion visibility and discrimination between NBI alone and NBI combined with TXI using previously stored gastrointestinal endoscopic images. Through this comparison, we sought to clarify the effectiveness of combining TXI with NBI and to contribute to improved diagnostic performance in clinical endoscopic practice. Basic objectives2 - Efficacy

Eligibility: Age-lower limit - Not applicable Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Neoplastic or non-neoplastic lesions identified during upper and lower gastrointestinal endoscopic examinations performed at our institution between August and September 2025 Key exclusion criteria - Unclear image quality, difficulty in defining the region of interest (ROI), incomplete clinical records, or withdrawal of consent (opt-out refusal) Target Size - 30

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 07 Month 20 Day Anticipated trial start date - 2025 Year 08 Month 01 Day Last follow-up date - 2025 Year 09 Month 30 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069122

Disclaimer: Curated by HT Syndication.