Japan, Feb. 27 -- BAILI BIO CHENGDU PHARMACEUTICAL CO LTD has got intellectual property rights for 'CAMPTOTHECIN DRUG AND ANTIBODY CONJUGATE THEREOF.' Other related details are as follows:
Application Number: JP,2024-002606
Category (FI): A61P35/00,A61K39/395@N,A61K31/4745,C07D491/22,A61K47/68
Stage: PROBLEM TO BE SOLVED: To provide a camptothecin drug and its antibody conjugate.SOLUTION: The present invention provides a compound of the formula I (where, R1 and R2 are independently selected from the group consisting of a C1-C3 alkyl group, a substituted alkyl group, -H, -CF3, an aryl group, a substituted aryl group and a heteroaryl group, or R1 and R2 form a ring structure together with carbon atoms bound to them, provided that R1 and R2 are not both hydrogen at the same time) and an antibody-drug conjugate of the formula II (where, Ab represents an antibody, an antibody fragment or a protein, L represents a linker, and D represents the compound of formula I).SELECTED DRAWING: None (Grant)
Filing Date: Jan. 11, 2024
Publication Date: April 10, 2024
The original document can be viewed at: https://www.j-platpat.inpit.go.jp/p0100
Disclaimer: Curated by HT Syndication.
