Japan, Feb. 27 -- GODO SHIGEN CO LTD,UNIV CHIBA NAT UNIV CORP has got intellectual property rights for 'METHOD OF MANUFACTURING TETRAFLUOROIODOBENZYL BROMIDE.' Other related details are as follows:

Application Number: JP,2022-044612

Category (FI): C07B53/00@B,C07C17/16,C07C227/04,C07C227/18,C07C229/36,C07C25/13

Stage: PROBLEM TO BE SOLVED: To produce optically active tetrafluoroiodophenylalanine using a highly versatile and simple process.SOLUTION: Tetrafluoroiodobenzoic acid is produced by mixing tetrafluorobenzoic acid with an iodine solution and n-BuLi, and tetrafluoroiodobenzyl alcohol is produced by mixing the resultant tetrafluoroiodobenzoic acid with a boron reagent, and tetrafluoroiodophenylalanine is produced by mixing the resultant tetrafluoroiodobenzyl alcohol with CBr4 and PPh3 or PBr3.SELECTED DRAWING: None (Grant)

Filing Date: March 18, 2022

Publication Date: Sept. 29, 2023

The original document can be viewed at: https://www.j-platpat.inpit.go.jp/p0100

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